Immobilized Osteopontin Enhances Adhesion but Suppresses Cytokine Release of Anti-IgE Activated Human Mast Cells

Osteopontin (OPN) is an Arg-Gly-Asp (RGD)-containing extracellular matrix protein which is upregulated in inflamed tissues and has been reported to modulate mast cell activities in mice. Due to the known heterogeneity among mast cells of different species and the important roles of mast cells in all...

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Udgivet i:Front Immunol
Main Authors: Ng, Chun Wai, Tam, Issan Yee San, Sam, Sze Wing, Yu, Yangyang, Lau, Hang Yung Alaster
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972195/
https://ncbi.nlm.nih.gov/pubmed/29872439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01109
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