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Differential Effects of the Toll-Like Receptor 2 Agonists, PGN and Pam3CSK4 on Anti-IgE Induced Human Mast Cell Activation

Mast cells are pivotal in the pathogenesis of allergy and inflammation. In addition to the classical IgE-dependent mechanism involving crosslinking of the high-affinity receptor for IgE (FcεRI), mast cells are also activated by Toll-like receptors (TLRs) which are at the center of innate immunity. I...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yu, Yangyang, Yip, Kwok Ho, Tam, Issan Yee San, Sam, Sze Wing, Ng, Chun Wai, Zhang, Wei, Lau, Hang Yung Alaster
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4232580/
https://ncbi.nlm.nih.gov/pubmed/25398056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112989
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