Simvastatin Inhibits Activation of NADPH Oxidase/p38 MAPK Pathway and Enhances Expression of Antioxidant Protein in Parkinson Disease Models

Evidence suggests that oxidative stress is involved in the pathogenesis of Parkinson disease (PD). Simvastatin has been suggested to protect against oxidative stress in several diseases. However, the molecular mechanisms by which simvastatin protects against neuropathology and oxidative damage in PD...

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Opis bibliograficzny
Wydane w:Front Mol Neurosci
Główni autorzy: Tong, Huichun, Zhang, Xiuping, Meng, Xingjun, Lu, Lingli, Mai, Dongmei, Qu, Shaogang
Format: Artigo
Język:Inglês
Wydane: Frontiers Media S.A. 2018
Hasła przedmiotowe:
Neuroscience
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972184/
https://ncbi.nlm.nih.gov/pubmed/29872377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00165
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