Simvastatin Inhibits Activation of NADPH Oxidase/p38 MAPK Pathway and Enhances Expression of Antioxidant Protein in Parkinson Disease Models

Evidence suggests that oxidative stress is involved in the pathogenesis of Parkinson disease (PD). Simvastatin has been suggested to protect against oxidative stress in several diseases. However, the molecular mechanisms by which simvastatin protects against neuropathology and oxidative damage in PD...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Tong, Huichun, Zhang, Xiuping, Meng, Xingjun, Lu, Lingli, Mai, Dongmei, Qu, Shaogang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972184/
https://ncbi.nlm.nih.gov/pubmed/29872377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00165
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