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Comparison of a Rat Primary Cell-Based Blood-Brain Barrier Model With Epithelial and Brain Endothelial Cell Lines: Gene Expression and Drug Transport

Cell culture-based blood-brain barrier (BBB) models are useful tools for screening of CNS drug candidates. Cell sources for BBB models include primary brain endothelial cells or immortalized brain endothelial cell lines. Despite their well-known differences, epithelial cell lines are also used as su...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Veszelka, Szilvia, Tóth, András, Walter, Fruzsina R., Tóth, Andrea E., Gróf, Ilona, Mészáros, Mária, Bocsik, Alexandra, Hellinger, Éva, Vastag, Monika, Rákhely, Gábor, Deli, Mária A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972182/
https://ncbi.nlm.nih.gov/pubmed/29872378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2018.00166
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