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Dual TGF-β and PD-1 blockade: a strategy for immune-excluded tumors?
Tumors that elude infiltration by CD8(+) T lymphocytes are particularly resistant to multiple forms of treatment, including immune checkpoint blockade. Stromal TGF-β appears to play a key role in this process, potentially constituting a target for novel combinatorial regimens tackling immune-exclude...
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| 出版年: | Trends Immunol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5972064/ https://ncbi.nlm.nih.gov/pubmed/29598848 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2018.03.002 |
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