Increased HCN Channel Activity in the Gasserian Ganglion Contributes to Trigeminal Neuropathic Pain

Orofacial neuropathic pain caused by trigeminal nerve injury is a debilitating condition with limited therapeutic options. Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate neuronal excitability and are involved in the development and maintenance of chronic pain. However, t...

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Veröffentlicht in:J Pain
Hauptverfasser: Ding, Weihua, You, Zerong, Shen, Shiqian, Yang, Jinsheng, Grewo, Lim, Doheny, Jason T, Zhu, Shengmei, Zhang, Yi, Chen, Lucy, Mao, Jianren
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5972061/
https://ncbi.nlm.nih.gov/pubmed/29366880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpain.2018.01.003
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