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Methylphenidate and Morphine Combination Therapy in a Rat Model of Chronic Pain
BACKGROUND: The incremental dose of opioids used in chronic pain management often leads to a reduced opioid analgesic effect, opioid misuse and addiction. Central dopamine dysfunction contributes to the chronicity of pain and a decreased opioid analgesic effect. Methylphenidate (MPH/Ritalin) enhance...
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| Publicado no: | Anesth Analg |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7646954/ https://ncbi.nlm.nih.gov/pubmed/31206430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0000000000004273 |
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