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CD38 produces nicotinic acid adenosine dinucleotide phosphate in the lysosome

Nicotinic acid adenosine dinucleotide phosphate (NAADP) is a Ca(2+)-mobilizing second messenger that regulates a wide range of biological activities. However, the mechanism of its biogenesis remains controversial. CD38 is the only enzyme known to catalyze NAADP synthesis from NADP and nicotinic acid...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Fang, Cheng, Li, Ting, Li, Ying, Xu, Guan Jie, Deng, Qi Wen, Chen, Ya Jie, Hou, Yun Nan, Lee, Hon Cheung, Zhao, Yong Juan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971459/
https://ncbi.nlm.nih.gov/pubmed/29632067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002113
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