TOR complex 2 in fission yeast is required for chromatin-mediated gene silencing and assembly of heterochromatic domains at subtelomeres

The conserved serine/threonine protein kinase target of rapamycin (TOR) is a major regulator of eukaryotic cellular and organismal growth and a valuable target for drug therapy. TOR forms the core of two evolutionary conserved complexes, TOR complex 1 (TORC1) and TORC2. In the fission yeast Schizosa...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Cohen, Adiel, Habib, Aline, Laor, Dana, Yadav, Sudhanshu, Kupiec, Martin, Weisman, Ronit
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2018
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5971458/
https://ncbi.nlm.nih.gov/pubmed/29632066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002270
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