A PAX5-OCT4-PRDM1 Developmental Switch Specifies Human Primordial Germ Cells

Dysregulation of genetic pathways during human germ cell development leads to infertility. Here, we analyzed bona fide human primordial germ cells (hPGCs) to probe the developmental genetics of human germ cell specification and differentiation. We examined distribution of OCT4 occupancy in hPGCs rel...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nat Cell Biol
Autors principals: Fang, Fang, Angulo, Benjamin, Xia, Ninuo, Sukhwani, Meena, Wang, Zhengyuan, Carey, Charles C, Mazurie, Aurélien, Cui, Jun, Wilkinson, Royce, Wiedenheft, Blake, Irie, Naoko, Surani, M. Azim, Orwig, Kyle E, Pera, Renee A Reijo
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970969/
https://ncbi.nlm.nih.gov/pubmed/29713018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0094-3
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars