A PAX5-OCT4-PRDM1 Developmental Switch Specifies Human Primordial Germ Cells

Dysregulation of genetic pathways during human germ cell development leads to infertility. Here, we analyzed bona fide human primordial germ cells (hPGCs) to probe the developmental genetics of human germ cell specification and differentiation. We examined distribution of OCT4 occupancy in hPGCs rel...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Fang, Fang, Angulo, Benjamin, Xia, Ninuo, Sukhwani, Meena, Wang, Zhengyuan, Carey, Charles C, Mazurie, Aurélien, Cui, Jun, Wilkinson, Royce, Wiedenheft, Blake, Irie, Naoko, Surani, M. Azim, Orwig, Kyle E, Pera, Renee A Reijo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970969/
https://ncbi.nlm.nih.gov/pubmed/29713018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0094-3
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados