Nalaganje...
Metabolically-derived lysine acylations and neighboring modifications tune BET bromodomain binding to histone H4
Recent proteomic studies discovered histone lysines are modified by acylations beyond acetylation. These acylations derive from acyl-CoA metabolites, potentially linking metabolism to transcription. Bromodomains bind lysine acylation on histones and other nuclear proteins to influence transcription....
Shranjeno v:
| izdano v: | Biochemistry |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2017
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5970795/ https://ncbi.nlm.nih.gov/pubmed/28945351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00595 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|