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Indomethacin promotes survival of new neurons in the adult murine hippocampus accompanied by anti-inflammatory effects following MPTP-induced dopamine depletion

BACKGROUND: Parkinson’s disease (PD) is characterized by dopaminergic cell loss and inflammation in the substantia nigra (SN) leading to motor deficits but also to hippocampus-associated non-motor symptoms such as spatial learning and memory deficits. The cognitive decline is correlated with impaire...

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Bibliografiske detaljer
Udgivet i:J Neuroinflammation
Main Authors: Hain, Elisabeth G., Sparenberg, Maria, Rasińska, Justyna, Klein, Charlotte, Akyüz, Levent, Steiner, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970532/
https://ncbi.nlm.nih.gov/pubmed/29803225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-018-1179-4
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