25-Hydroxyvitamin D Depletion Does Not Exacerbate MPTP-Induced Dopamine Neuron Damage in Mice

Recent clinical evidence supports a link between 25-hydroxyvitamin D insufficiency (serum 25-hydroxyvitamin D [25(OH)D] levels <30 ng/mL) and Parkinson’s disease. To investigate the effect of 25(OH)D depletion on neuronal susceptibility to toxic insult, we induced a state of 25(OH)D deficiency in...

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Autors principals: Dean, E. Danielle, Mexas, Lydia M., Cápiro, Natalie L., McKeon, Jeanne E., DeLong, Mahlon R., Pennell, Kurt D., Doorn, Jonathan A., Tangpricha, Vin, Miller, Gary W., Evatt, Marian L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388077/
https://ncbi.nlm.nih.gov/pubmed/22768297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039227
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