Serum Autotaxin Is a Useful Disease Progression Marker in Patients with Primary Biliary Cholangitis

Autotaxin (ATX) is a secreted enzyme metabolized by liver sinusoidal endothelial cells that has been associated with liver fibrosis. We evaluated serum ATX values in 128 treatment-naïve, histologically assessed primary biliary cholangitis (PBC) patients and 80 healthy controls for comparisons of cli...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Joshita, Satoru, Umemura, Takeji, Usami, Yoko, Yamashita, Yuki, Norman, Gary L., Sugiura, Ayumi, Yamazaki, Tomoo, Fujimori, Naoyuki, Kimura, Takefumi, Matsumoto, Akihiro, Igarashi, Koji, Yoshizawa, Kaname, Ota, Masao, Tanaka, Eiji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970155/
https://ncbi.nlm.nih.gov/pubmed/29802350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26531-0
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