Genetic Association of PTPN22 Polymorphisms with Autoimmune Hepatitis and Primary Biliary Cholangitis in Japan

Autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) are liver-specific autoimmune conditions that are characterized by chronic hepatic damage and often lead to cirrhosis and hepatic failure. Specifically, the protein tyrosine phosphatase N22 (PTPN22) gene encodes the lymphoid protein ty...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Umemura, Takeji, Joshita, Satoru, Yamazaki, Tomoo, Komatsu, Michiharu, Katsuyama, Yoshihiko, Yoshizawa, Kaname, Tanaka, Eiji, Ota, Masao
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942688/
https://ncbi.nlm.nih.gov/pubmed/27406031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29770
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