Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex

The unfolded protein response (UPR) pathway, consisting of the evolutionarily conserved Ire1 kinase/endonuclease and the bZIP transcription factor Hxl1, is critical for the pathogenicity of Cryptococcus neoformans; however, its role remains unknown in other pathogenic Cryptococcus species. Here, we...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Jung, Kwang-Woo, Lee, Kyung-Tae, Averette, Anna F., Hoy, Michael J., Everitt, Jeffrey, Heitman, Joseph, Bahn, Yong-Sun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970146/
https://ncbi.nlm.nih.gov/pubmed/29802329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26405-5
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