Unique Evolution of the UPR Pathway with a Novel bZIP Transcription Factor, Hxl1, for Controlling Pathogenicity of Cryptococcus neoformans

In eukaryotic cells, the unfolded protein response (UPR) pathway plays a crucial role in cellular homeostasis of the endoplasmic reticulum (ER) during exposure to diverse environmental conditions that cause ER stress. Here we report that the human fungal pathogen Cryptococcus neoformans has evolved...

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Main Authors: Cheon, Seon Ah, Jung, Kwang-Woo, Chen, Ying-Lien, Heitman, Joseph, Bahn, Yong-Sun, Kang, Hyun Ah
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154848/
https://ncbi.nlm.nih.gov/pubmed/21852949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002177
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