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Synthesis of native-like crosslinked duplex RNA and study of its properties

A variety of enzymes have been found to interact with double-stranded RNA (dsRNA) in order to carry out its functions. We have endeavored to prepare the covalently crosslinked native-like duplex RNA, which could be useful for biochemical studies and RNA nanotechnology. In this study, the interstrand...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Onizuka, Kazumitsu, Hazemi, Madoka E., Thomas, Justin M., Monteleone, Leanna R., Yamada, Ken, Imoto, Shuhei, Beal, Peter A., Nagatsugi, Fumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969911/
https://ncbi.nlm.nih.gov/pubmed/28268052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.02.034
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