Reactive OFF-ON type alkylating agents for higher-ordered structures of nucleic acids

Higher-ordered structure motifs of nucleic acids, such as the G-quadruplex (G-4), mismatched and bulge structures, are significant research targets because these structures are involved in genetic control and diseases. Selective alkylation of these higher-order structures is challenging due to the c...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Onizuka, Kazumitsu, Hazemi, Madoka E, Sato, Norihiro, Tsuji, Gen-ichiro, Ishikawa, Shunya, Ozawa, Mamiko, Tanno, Kousuke, Yamada, Ken, Nagatsugi, Fumi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Chemical Biology and Nucleic Acid Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6649768/
https://ncbi.nlm.nih.gov/pubmed/31188442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz512
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