Pharmacokinetics of rifapentine and rifampin in a rabbit model of tuberculosis and correlation with clinical trial data

In clinical trials of two rifamycin antibiotics (rifampin and rifapentine) for treating tuberculosis (TB), patients with cavitary lung lesions did not appear to derive benefit from rifapentine. Rifapentine was found not to outperform rifampin, despite a lower minimum inhibitory concentration against...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Sci Transl Med
Hlavní autoři: Rifat, Dalin, Prideaux, Brendan, Savic, Radojka M., Urbanowski, Michael E., Parsons, Teresa L., Luna, Brian, Marzinke, Mark A., Ordonez, Alvaro A., DeMarco, Vincent P., Jain, Sanjay K., Dartois, Veronique, Bishai, William R., Dooley, Kelly E.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969904/
https://ncbi.nlm.nih.gov/pubmed/29618565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aai7786
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky