Regulator of calcineurin 1 differentially regulates TLR-dependent MyD88 and TRIF signaling pathways

Toll-like receptors (TLRs) recognize the conserved molecular patterns in microorganisms and trigger myeloid differentiation primary response 88 (MyD88) and/or TIR-domain-containing adapter-inducing interferon-β (TRIF) pathways that are critical for host defense against microbial infection. However,...

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Udgivet i:PLoS One
Main Authors: Pang, Zheng, Junkins, Robert D., Raudonis, Renee, MacNeil, Adam J., McCormick, Craig, Cheng, Zhenyu, Lin, Tong-Jun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969770/
https://ncbi.nlm.nih.gov/pubmed/29799862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0197491
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