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Multiplexed enrichment of rare DNA variants via sequence-selective and temperature-robust amplification
Rare DNA-sequence variants hold important clinical and biological information, but existing detection techniques are expensive, complex, allele-specific, or don’t allow for significant multiplexing. Here, we report a temperature-robust polymerase-chain-reaction method, which we term blocker displace...
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| Publicat a: | Nat Biomed Eng |
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| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5969535/ https://ncbi.nlm.nih.gov/pubmed/29805844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41551-017-0126-5 |
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