CD14(+) CD15(−) HLA-DR(−) myeloid-derived suppressor cells impair antimicrobial responses in patients with acute-on-chronic liver failure

OBJECTIVE: Immune paresis in patients with acute-on-chronic liver failure (ACLF) accounts for infection susceptibility and increased mortality. Immunosuppressive mononuclear CD14(+)HLA-DR(−) myeloid-derived suppressor cells (M-MDSCs) have recently been identified to quell antimicrobial responses in...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Bernsmeier, Christine, Triantafyllou, Evangelos, Brenig, Robert, Lebosse, Fanny J, Singanayagam, Arjuna, Patel, Vishal C, Pop, Oltin T, Khamri, Wafa, Nathwani, Rooshi, Tidswell, Robert, Weston, Christopher J, Adams, David H, Thursz, Mark R, Wendon, Julia A, Antoniades, Charalambos Gustav
Formato: Artigo
Idioma:Inglês
Publicado em: Gut 2018
Assuntos:
Hepatology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969362/
https://ncbi.nlm.nih.gov/pubmed/28592438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-314184
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