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Protecting‐Group‐Free Amidation of Amino Acids using Lewis Acid Catalysts

Amidation of unprotected amino acids has been investigated using a variety of ‘classical“ coupling reagents, stoichiometric or catalytic group(IV) metal salts, and boron Lewis acids. The scope of the reaction was explored through the attempted synthesis of amides derived from twenty natural, and sev...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Sabatini, Marco T., Karaluka, Valerija, Lanigan, Rachel M., Boulton, Lee T., Badland, Matthew, Sheppard, Tom D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5969221/
https://ncbi.nlm.nih.gov/pubmed/29505683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201800372
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