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Design and preparation of derivatives of oleanolic and glycyrrhetinic acids with cytotoxic properties

BACKGROUND: The structural modification of natural products with the aim to improve the anticancer activity is a popular current research direction. The pentacyclic triterpenoid compounds oleanolic acid (OA) and glycyrrhetinic acid (GA) are distributed widely in nature. METHODS: In this study, vario...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wang, Rui, Li, Yang, Huai, Xu-Dong, Zheng, Qing-Xuan, Wang, Wei, Li, Hui-Jing, Huai, Qi-Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968802/
https://ncbi.nlm.nih.gov/pubmed/29861624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S166051
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