Using high throughput microtissue culture to study the difference in prostate cancer cell behavior and drug response in 2D and 3D co-cultures

BACKGROUND: There is increasing appreciation that non-cancer cells within the tumour microenvironment influence cancer progression and anti-cancer drug efficacy. For metastatic prostate cancer (PCa), the bone marrow microenvironment influences metastasis, drug response, and possibly drug resistance....

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Vydáno v:BMC Cancer
Hlavní autoři: Mosaad, Eman, Chambers, Karen, Futrega, Kathryn, Clements, Judith, Doran, Michael Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5968610/
https://ncbi.nlm.nih.gov/pubmed/29793440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4473-8
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