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3D Cultures of Prostate Cancer Cells Cultured in a Novel High-Throughput Culture Platform Are More Resistant to Chemotherapeutics Compared to Cells Cultured in Monolayer

Despite monolayer cultures being widely used for cancer drug development and testing, 2D cultures tend to be hypersensitive to chemotherapy and are relatively poor predictors of whether a drug will provide clinical benefit. Whilst generally more complicated, three dimensional (3D) culture systems of...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Chambers, Karen F., Mosaad, Eman M. O., Russell, Pamela J., Clements, Judith A., Doran, Michael R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224379/
https://ncbi.nlm.nih.gov/pubmed/25380249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111029
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