Chitosan-Mangafodipir nanoparticles designed for intranasal delivery of siRNA and DNA to brain

The overall objective of the present research was to develop a nanocarrier system for non-invasive delivery to brain of molecules useful for gene therapy. Manganese-containing nanoparticles (mNPs) carrying anti-eGFP siRNA were tested in cell cultures of eGFP-expressing cell line of mouse fibroblasts...

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Publicado en:J Drug Deliv Sci Technol
Autores principales: Sanchez-Ramos, Juan, Song, Shijie, Kong, Xiaoyuan, Foroutan, Parastou, Martinez, Gary, Dominguez-Viqueria, William, Mohapatra, Shyam, Mohapatra, Subhra, Haraszti, Reka A., Khvorova, Anastasia, Aronin, Neil, Sava, Vasyl
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967853/
https://ncbi.nlm.nih.gov/pubmed/29805475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jddst.2017.11.013
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