The Most N-Terminal Region of THSD7A Is the Predominant Target for Autoimmunity in THSD7A-Associated Membranous Nephropathy

Background Thrombospondin type 1 domain–containing 7A (THSD7A) has been identified as a pathogenic autoantigen in membranous nephropathy (MN). However, the THSD7A epitopes targeted by patient autoantibodies are unknown. Methods We performed an in silico analysis of the THSD7A multidomain structure,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Am Soc Nephrol
मुख्य लेखकों: Seifert, Larissa, Hoxha, Elion, Eichhoff, Anna M., Zahner, Gunther, Dehde, Silke, Reinhard, Linda, Koch-Nolte, Friedrich, Stahl, Rolf A.K., Tomas, Nicola M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society of Nephrology 2018
विषय:
Clinical Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967759/
https://ncbi.nlm.nih.gov/pubmed/29555830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017070805
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