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Autoantibodies against thrombospondin type 1 domain–containing 7A induce membranous nephropathy

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults, and one-third of patients develop end-stage renal disease (ESRD). Circulating autoantibodies against the podocyte surface antigens phospholipase A(2) receptor 1 (PLA(2)R1) and the recently identified thrombospondin...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Tomas, Nicola M., Hoxha, Elion, Reinicke, Anna T., Fester, Lars, Helmchen, Udo, Gerth, Jens, Bachmann, Friederike, Budde, Klemens, Koch-Nolte, Friedrich, Zahner, Gunther, Rune, Gabriele, Lambeau, Gerard, Meyer-Schwesinger, Catherine, Stahl, Rolf A.K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922694/
https://ncbi.nlm.nih.gov/pubmed/27214550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85265
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