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Chronic Intermittent Hypoxia Causes Lipid Peroxidation and Altered Phase 1 Drug Metabolizing Enzymes in the Neonatal Rat Liver

Critically ill preterm neonates requiring oxygen therapy often experience frequent apneas with intermittent hypoxia (IH). IH-induced oxidative stress causes lipid peroxidation, which targets the liver and contributes to toxic drug reactions. We tested the hypothesis that incremental IH episodes indu...

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Detalhes bibliográficos
Publicado no:React Oxyg Species (Apex)
Main Authors: Cai, Charles, Aranda, Jacob V., Valencia, Gloria B., Xu, Jiliu, Beharry, Kay D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967640/
https://ncbi.nlm.nih.gov/pubmed/29806035
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