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Hydrogen Peroxide Accumulation in the Choroid During Intermittent Hypoxia Increases Risk of Severe Oxygen-Induced Retinopathy in Neonatal Rats

PURPOSE. Extremely low gestational age neonates (ELGANs) requiring oxygen therapy often experience frequent episodes of intermittent hypoxia (IH) and are at high risk for severe retinopathy of prematurity (ROP). Using an established model for oxygen-induced retinopathy (OIR), we examined the hypothe...

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Bibliographic Details
Main Authors: Beharry, Kay D., Cai, Charles L., Sharma, Poonam, Bronshtein, Vadim, Valencia, Gloria B., Lazzaro, Douglas R., Aranda, Jacob V.
Format: Artigo
Language:Inglês
Published: The Association for Research in Vision and Ophthalmology 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3835271/
https://ncbi.nlm.nih.gov/pubmed/24168990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-13040
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