Ocular Adverse Effects of Intravitreal Bevacizumab Are Potentiated by Intermittent Hypoxia in a Rat Model of Oxygen-Induced Retinopathy

Intravitreal bevacizumab (Avastin) use in preterm infants with retinopathy of prematurity is associated with severe neurological disabilities, suggesting vascular leakage. We examined the hypothesis that intermittent hypoxia (IH) potentiates intravitreal Avastin leakage. Neonatal rats at birth were...

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Bibliographic Details
Published in:J Ophthalmol
Main Authors: Tan, Jeffrey J., Cai, Charles L., Shrier, Eric M., McNally, Lois, Lazzaro, Douglas R., Aranda, Jacob V., Beharry, Kay D.
Format: Artigo
Language:Inglês
Published: Hindawi 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5523466/
https://ncbi.nlm.nih.gov/pubmed/28770109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/4353129
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