Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain

The cyclic nucleotides cAMP and cGMP are important second messengers that orchestrate fundamental cellular responses. Here, we present the characterization of the rhodopsin-guanylyl cyclase from Catenaria anguillulae (CaRhGC), which produces cGMP in response to green light with a light to dark activ...

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發表在:Nat Commun
Main Authors: Scheib, Ulrike, Broser, Matthias, Constantin, Oana M., Yang, Shang, Gao, Shiqiang, Mukherjee, Shatanik, Stehfest, Katja, Nagel, Georg, Gee, Christine E., Hegemann, Peter
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967339/
https://ncbi.nlm.nih.gov/pubmed/29799525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04428-w
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