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Synthesis of E- and Z-trisubstituted alkenes by catalytic cross-metathesis

Catalytic cross-metathesis is a central transformation in chemistry, and yet, corresponding methods for stereoselectively generating acyclic trisubstituted alkenes in either isomeric form do not exist. The key problems are lack of chemoselectivity, namely, the preponderance of side reactions involvi...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Nguyen, Thach T., Koh, Ming Joo, Mann, Tyler J., Schrock, Richard R., Hoveyda, Amir H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967255/
https://ncbi.nlm.nih.gov/pubmed/29293209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25002
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