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E- and Z-, Di-, and trisubstituted alkenyl nitriles through catalytic cross-metathesis

Nitriles are found in many bioactive compounds, and are among the most versatile functional groups in organic chemistry. Despite many notable recent advances, however, there are no approaches that may be used for preparation of di- or trisubstituted alkenyl nitriles. Related approaches which are bro...

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Publicat a:Nat Chem
Autors principals: Mu, Yucheng, Nguyen, Thach T., Koh, Ming Joo, Schrock, Richard R., Hoveyda, Amir H.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6538264/
https://ncbi.nlm.nih.gov/pubmed/30936524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-019-0233-x
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