Bulleyaconitine A attenuates hyperexcitability of dorsal root ganglion neurons induced by spared nerve injury: The role of preferably blocking Nav1.7 and Nav1.3 channels

BACKGROUND: Oral administration of Bulleyaconitine A, an extracted diterpenoid alkaloid from Aconitum bulleyanum plants, is effective for treating chronic pain in rats and in human patients, but the underlying mechanisms are poorly understood. RESULTS: As the hyperexcitability of dorsal root ganglio...

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Detalhes bibliográficos
Publicado no:Mol Pain
Main Authors: Xie, Man-Xiu, Yang, Jie, Pang, Rui-Ping, Zeng, Wei-An, Ouyang, Han-Dong, Liu, Yan-Qing, Liu, Xian-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967161/
https://ncbi.nlm.nih.gov/pubmed/29783906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1744806918778491
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