Conserved Expression of Nav1.7 and Nav1.8 Contribute to the Spontaneous and Thermally Evoked Excitability in IL-6 and NGF-Sensitized Adult Dorsal Root Ganglion Neurons In Vitro

Sensory neurons respond to noxious stimuli by relaying information from the periphery to the central nervous system via action potentials driven by voltage-gated sodium channels, specifically Nav1.7 and Nav1.8. These channels play a key role in the manifestation of inflammatory pain. The ability to...

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Vydáno v:Bioengineering (Basel)
Hlavní autoři: Atmaramani, Rahul R., Black, Bryan J., de la Peña, June Bryan, Campbell, Zachary T., Pancrazio, Joseph J.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7356605/
https://ncbi.nlm.nih.gov/pubmed/32429423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/bioengineering7020044
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