Xanthine oxidase inhibitors and sepsis

Xanthine oxidase activation occurs in sepsis and results in the generation of uric acid (UrAc) and reactive oxygen species (ROS). We aimed to evaluate the effect of xanthine oxidase inhibitors (XOis) in rats stimulated with lipopolysaccharide (LPS). LPS (10 mg/kg) was administered intraperitoneally...

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Publicado en:Int J Immunopathol Pharmacol
Autores principales: Ramos, Maria Fátima de Paula, Monteiro de Barros, Alceni do Carmo Morais, Razvickas, Clara Versolato, Borges, Fernanda T, Schor, Nestor
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2018
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Original Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5967155/
https://ncbi.nlm.nih.gov/pubmed/29786457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2058738418772210
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