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Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss

Hypoxia (low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation of hypoxia-inducible factor 1 (HIF-1). Hypoxia interferes degradation of HIF-1 alph...

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Bibliografiske detaljer
Udgivet i:Int J Oral Sci
Main Authors: Hirai, Kimito, Furusho, Hisako, Hirota, Kiichi, Sasaki, Hajime
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966812/
https://ncbi.nlm.nih.gov/pubmed/29654284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41368-018-0015-0
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