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Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss

Hypoxia (low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation of hypoxia-inducible factor 1 (HIF-1). Hypoxia interferes degradation of HIF-1 alph...

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Detalles Bibliográficos
Publicado en:Int J Oral Sci
Main Authors: Hirai, Kimito, Furusho, Hisako, Hirota, Kiichi, Sasaki, Hajime
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966812/
https://ncbi.nlm.nih.gov/pubmed/29654284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41368-018-0015-0
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