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Activation of hypoxia-inducible factor 1 attenuates periapical inflammation and bone loss

Hypoxia (low oxygen level) is an important feature during infections and affects the host defence mechanisms. The host has evolved specific responses to address hypoxia, which are strongly dependent on the activation of hypoxia-inducible factor 1 (HIF-1). Hypoxia interferes degradation of HIF-1 alph...

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Detalhes bibliográficos
Publicado no:Int J Oral Sci
Main Authors: Hirai, Kimito, Furusho, Hisako, Hirota, Kiichi, Sasaki, Hajime
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966812/
https://ncbi.nlm.nih.gov/pubmed/29654284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41368-018-0015-0
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