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Renal tubular ACE-mediated tubular injury is the major contributor to microalbuminuria in early diabetic nephropathy

Diabetic nephropathy is a major cause of end-stage renal disease in developed countries. While angiotensin-converting enzyme (ACE) inhibitors are used to treat diabetic nephropathy, how intrarenal ACE contributes to diabetic renal injury is uncertain. Here, two mouse models with different patterns o...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Eriguchi, Masahiro, Lin, Mercury, Yamashita, Michifumi, Zhao, Tuantuan V., Khan, Zakir, Bernstein, Ellen A., Gurley, Susan B., Gonzalez-Villalobos, Romer A., Bernstein, Kenneth E., Giani, Jorge F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966765/
https://ncbi.nlm.nih.gov/pubmed/29187372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00523.2017
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