Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils

Angiotensin-converting enzyme (ACE) inhibitors are widely used to reduce blood pressure. Here, we examined if an ACE is important for the antibacterial effectiveness of neutrophils. ACE knockout mice or mice treated with an ACE inhibitor were more susceptible to bacterial infection by methicillin-re...

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Bibliographische Detailangaben
Veröffentlicht in:Blood
Hauptverfasser: Khan, Zakir, Shen, Xiao Z., Bernstein, Ellen A., Giani, Jorge F., Eriguchi, Masahiro, Zhao, Tuantuan V., Gonzalez-Villalobos, Romer A., Fuchs, Sebastien, Liu, George Y., Bernstein, Kenneth E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Phagocytes, Granulocytes, and Myelopoiesis
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520468/
https://ncbi.nlm.nih.gov/pubmed/28515091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-752006
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