Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils

Angiotensin-converting enzyme (ACE) inhibitors are widely used to reduce blood pressure. Here, we examined if an ACE is important for the antibacterial effectiveness of neutrophils. ACE knockout mice or mice treated with an ACE inhibitor were more susceptible to bacterial infection by methicillin-re...

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Vydáno v:Blood
Hlavní autoři: Khan, Zakir, Shen, Xiao Z., Bernstein, Ellen A., Giani, Jorge F., Eriguchi, Masahiro, Zhao, Tuantuan V., Gonzalez-Villalobos, Romer A., Fuchs, Sebastien, Liu, George Y., Bernstein, Kenneth E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2017
Témata:
Phagocytes, Granulocytes, and Myelopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520468/
https://ncbi.nlm.nih.gov/pubmed/28515091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-752006
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