Angiotensin-converting enzyme enhances the oxidative response and bactericidal activity of neutrophils

Angiotensin-converting enzyme (ACE) inhibitors are widely used to reduce blood pressure. Here, we examined if an ACE is important for the antibacterial effectiveness of neutrophils. ACE knockout mice or mice treated with an ACE inhibitor were more susceptible to bacterial infection by methicillin-re...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Khan, Zakir, Shen, Xiao Z., Bernstein, Ellen A., Giani, Jorge F., Eriguchi, Masahiro, Zhao, Tuantuan V., Gonzalez-Villalobos, Romer A., Fuchs, Sebastien, Liu, George Y., Bernstein, Kenneth E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Phagocytes, Granulocytes, and Myelopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520468/
https://ncbi.nlm.nih.gov/pubmed/28515091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-11-752006
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