Testosterone protects high-fat/low-carbohydrate diet-induced nonalcoholic fatty liver disease in castrated male rats mainly via modulating endoplasmic reticulum stress

We previously showed that testosterone (T) deficiency enhanced high-fat/low-carbohydrate diet (HFD)-induced hepatic steatosis in rats independent of insulin resistance and that T replacement reduced hepatic macrovesicular fat accumulation and inflammation. The present report explores the mechanism o...

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Detalhes bibliográficos
Publicado no:Am J Physiol Endocrinol Metab
Main Authors: Jia, Yue, Yee, Jennifer K., Wang, Christina, Nikolaenko, Liana, Diaz-Arjonilla, Maruja, Cohen, Joshua N., French, Samuel W., Liu, Peter Y., Lue, YanHe, Lee, Wai-Nang P., Swerdloff, Ronald S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966753/
https://ncbi.nlm.nih.gov/pubmed/28928235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00124.2017
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