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Simple Methods and Rational Design for Enhancing Aptamer Sensitivity and Specificity
Aptamers are structured nucleic acid molecules that can bind to their targets with high affinity and specificity. However, conventional SELEX (Systematic Evolution of Ligands by EXponential enrichment) methods may not necessarily produce aptamers of desired affinity and specificity. Thus, to address...
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| Publicado no: | Front Mol Biosci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5966647/ https://ncbi.nlm.nih.gov/pubmed/29868605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00041 |
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