Endocrine and haemodynamic changes in resistant hypertension, and blood pressure responses to spironolactone or amiloride: the PATHWAY-2 mechanisms substudies

BACKGROUND: In the PATHWAY-2 study of resistant hypertension, spironolactone reduced blood pressure substantially more than conventional antihypertensive drugs. We did three substudies to assess the mechanisms underlying this superiority and the pathogenesis of resistant hypertension. METHODS: PATHW...

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Detalhes bibliográficos
Publicado no:Lancet Diabetes Endocrinol
Main Authors: Williams, Bryan, MacDonald, Thomas M, Morant, Steve V, Webb, David J, Sever, Peter, McInnes, Gordon T, Ford, Ian, Cruickshank, J Kennedy, Caulfield, Mark J, Padmanabhan, Sandosh, Mackenzie, Isla S, Salsbury, Jackie, Brown, Morris J
Formato: Artigo
Idioma:Inglês
Publicado em: The Lancet, Diabetes & Endocrinology 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966620/
https://ncbi.nlm.nih.gov/pubmed/29655877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S2213-8587(18)30071-8
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