The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8(+) T Cells but Promotes Colitis via CD4(+) T Cells

CXC chemokine receptor 3 (CXCR3), a receptor for the C-X-C motif chemokines (CXCL) CXCL9, CXCL10, and CXCL11, which not only plays a role in chemotaxis but also regulates differentiation and development of memory and effector T cell populations. Herein, we explored the function of CXCR3 in the modul...

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Vydáno v:Front Immunol
Hlavní autoři: Liu, Qing-Zhi, Ma, Wen-Tao, Yang, Jing-Bo, Zhao, Zhi-Bin, Yan, Kai, Yao, Yuan, Li, Liang, Miao, Qi, Gershwin, M. Eric, Lian, Zhe-Xiong
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966573/
https://ncbi.nlm.nih.gov/pubmed/29868034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01090
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