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Cholinergic activity is essential for maintaining the anterograde transport of Choline Acetyltransferase in Drosophila
Cholinergic activity is essential for cognitive functions and neuronal homeostasis. Choline Acetyltransferase (ChAT), a soluble protein that synthesizes acetylcholine at the presynaptic compartment, is transported in bulk in the axons by the heterotrimeric Kinesin-2 motor. Axonal transport of solubl...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5966444/ https://ncbi.nlm.nih.gov/pubmed/29795337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26176-z |
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